Mycophenolate mofetil hydrochloride

Modify Date: 2024-01-20 16:02:23

Mycophenolate mofetil hydrochloride structure	Common Name	Mycophenolate mofetil hydrochloride
	CAS Number	116680-01-4	Molecular Weight	469.96
	Density	1.222g/cm3	Boiling Point	637.6ºC at 760mmHg
	Molecular Formula	C₂₃H₃₂ClNO₇	Melting Point	N/A
	MSDS	N/A	Flash Point	339.4ºC

Use of Mycophenolate mofetil hydrochloride

Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC50s of 39 nM and 27 nM, respectively.

Name	2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate,hydrochloride

Description	Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC50s of 39 nM and 27 nM, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	Human Endogenous Metabolite
References	[1]. Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7. [2]. Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611. [3]. Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54.

Density	1.222g/cm3
Boiling Point	637.6ºC at 760mmHg
Molecular Formula	C₂₃H₃₂ClNO₇
Molecular Weight	469.96
Flash Point	339.4ºC
Exact Mass	469.18700
PSA	94.53000
LogP	3.26390
Vapour Pressure	7.51E-17mmHg at 25°C
Index of Refraction	1.557