Glycyrrhisoflavone

Modify Date: 2025-08-25 15:33:33

Glycyrrhisoflavone Structure
Glycyrrhisoflavone structure
Common Name Glycyrrhisoflavone
CAS Number 116709-70-7 Molecular Weight 354.353
Density 1.4±0.1 g/cm3 Boiling Point 631.9±55.0 °C at 760 mmHg
Molecular Formula C20H18O6 Melting Point N/A
MSDS N/A Flash Point 229.4±25.0 °C

 Use of Glycyrrhisoflavone


Glycyrrhisoflavone, an active prenylflavonoid, mainly derived from the extract of the roots of Glycyrrhiza uralensis Fisch.. Glycyrrhisoflavone inhibits α-glucosidase[1].

 Names

Name 3-(3,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl)-5,7-dihydroxy-4H-chromen-4-one
Synonym More Synonyms

 Glycyrrhisoflavone Biological Activity

Description Glycyrrhisoflavone, an active prenylflavonoid, mainly derived from the extract of the roots of Glycyrrhiza uralensis Fisch.. Glycyrrhisoflavone inhibits α-glucosidase[1].
Related Catalog
References

[1]. Li W, et al. Bioassay-guided isolation and quantification of the alpha-glucosidase inhibitory compound, glycyrrhisoflavone, from Glycyrrhiza uralensis. Nat Prod Commun. 2010 Jul;5(7):1049-53.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 631.9±55.0 °C at 760 mmHg
Molecular Formula C20H18O6
Molecular Weight 354.353
Flash Point 229.4±25.0 °C
Exact Mass 354.110352
PSA 111.13000
LogP 4.85
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.690
InChIKey JOQWUUJQWPZLAT-UHFFFAOYSA-N
SMILES CC(C)=CCc1cc(-c2coc3cc(O)cc(O)c3c2=O)cc(O)c1O
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 GlycyrrhisoflavoneBioassay

View more

Name: Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate at 1...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 1
External Id: CHEMBL4035961
Name: Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4035959
Name: Inhibition of Bacillus subtilis N-terminal hexahistidine-tagged FtsZ GTPase activity ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3999567
Name: Inhibition of Escherichia coli N-terminal hexahistidine-tagged FtsZ GTPase activity e...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3999566
Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induc...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL4035957
Name: Activation of Nrf2 (unknown origin) expressed in human HepG2 cells at 10 uM incubated...
Source: ChEMBL
Target: Nuclear factor erythroid 2-related factor 2
External Id: CHEMBL4046717
Name: Growth inhibition of human HepG2 cells at 10 uM after 24 hrs by MTS assay relative to...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4035954
Name: HIV Enzyme Data
Source: NIAID
Target: N/A
External Id: HIV Enzyme Data
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Inhibition of mushroom tyrosinase at 10 uM using L-tyrosine as substrate incubated fo...
Source: ChEMBL
Target: Polyphenol oxidase 4
External Id: CHEMBL4035963
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 Synonyms

3-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-4H-chromen-4-one
Glycyrrh-iso-flavone
Glycyrrhisoflavone
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