1,7-Bis-Boc-1,4,7-triazaheptane

Modify Date: 2024-01-27 21:27:50

1,7-Bis-Boc-1,4,7-triazaheptane Structure
1,7-Bis-Boc-1,4,7-triazaheptane structure
 Common Name 1,7-Bis-Boc-1,4,7-triazaheptane
CAS Number 117499-16-8 Molecular Weight 303.39800
Density 1.0±0.1g/cm3 Boiling Point 440.5±30.0°C at 760 mmHg
Molecular Formula C14H29N3O4 Melting Point N/A
MSDS N/A Flash Point 220.2±24.6°C

 Use of 1,7-Bis-Boc-1,4,7-triazaheptane


1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate
Synonym More Synonyms

 1,7-Bis-Boc-1,4,7-triazaheptane Biological Activity

Description 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.0±0.1g/cm3
Boiling Point 440.5±30.0°C at 760 mmHg
Molecular Formula C14H29N3O4
Molecular Weight 303.39800
Flash Point 220.2±24.6°C
Exact Mass 303.21600
PSA 88.69000
LogP 2.79810
Index of Refraction 1.466
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
HS Code 2924199090

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1,7-Bis-Boc-1,4,7-triazaheptane
Bis(2-Methyl-2-Propanyl) (Iminodi-2,1-Ethanediyl)Biscarbamate
Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate
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Chemsrc provides 1,7-Bis-Boc-1,4,7-triazaheptane(CAS#:117499-16-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 1,7-Bis-Boc-1,4,7-triazaheptane are included as well.>> amp version: 1,7-Bis-Boc-1,4,7-triazaheptane

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