Z-505 hydrochloride
Modify Date: 2024-01-18 19:05:30
Z-505 hydrochloride structure
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Common Name | Z-505 hydrochloride | ||
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| CAS Number | 1179341-97-9 | Molecular Weight | 576.153 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H38ClN5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Z-505 hydrochlorideZ-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively;attenuates the progression of cancer cachexia via anabolic hormones in vivo, significantly improves the cisplatin-induced reduction in food intake and body weight, prevents the 5-FU-induced decrease in food intake and body weight in the 5-FU-induced mouse model. |
| Name | Z-505 hydrochloride |
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| Description | Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively;attenuates the progression of cancer cachexia via anabolic hormones in vivo, significantly improves the cisplatin-induced reduction in food intake and body weight, prevents the 5-FU-induced decrease in food intake and body weight in the 5-FU-induced mouse model. |
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| References | References 1. Shiomi Y, et al. Eur J Pharmacol. 2018 Jan 5;818:148-157. 2. Yoshimura M, et al. Eur J Pharmacol. 2017 Sep 15;811:30-37. View Related Products by Target Ghrelin Receptor (GHSR) |
| Molecular Formula | C28H38ClN5O4S |
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| Molecular Weight | 576.153 |