1179341-97-9
1179341-97-9 structure
- Name: Z-505 hydrochloride
- Chemical Name: Z-505 hydrochloride
- CAS Number: 1179341-97-9
- Molecular Formula: C28H38ClN5O4S
- Molecular Weight: 576.153
- Create Date: 2020-01-20 15:41:57
- Modify Date: 2024-01-18 19:05:30
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Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively;attenuates the progression of cancer cachexia via anabolic hormones in vivo, significantly improves the cisplatin-induced reduction in food intake and body weight, prevents the 5-FU-induced decrease in food intake and body weight in the 5-FU-induced mouse model.
| Name | Z-505 hydrochloride |
|---|
| Description | Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively;attenuates the progression of cancer cachexia via anabolic hormones in vivo, significantly improves the cisplatin-induced reduction in food intake and body weight, prevents the 5-FU-induced decrease in food intake and body weight in the 5-FU-induced mouse model. |
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| References | References 1. Shiomi Y, et al. Eur J Pharmacol. 2018 Jan 5;818:148-157. 2. Yoshimura M, et al. Eur J Pharmacol. 2017 Sep 15;811:30-37. View Related Products by Target Ghrelin Receptor (GHSR) |
| Molecular Formula | C28H38ClN5O4S |
|---|---|
| Molecular Weight | 576.153 |