Amylin (20-29) (human)

Modify Date: 2024-01-10 19:41:50

Amylin (20-29) (human) structure	Common Name	Amylin (20-29) (human)
	CAS Number	118068-30-7	Molecular Weight	1009.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₃H₆₈N₁₂O₁₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Amylin (20-29) (human)

Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors[1][2].

Name	h-ser-asn-asn-phe-gly-ala-ile-leu-ser-ser-oh
Synonym	More Synonyms

Description	Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Kapurniotu A, et al. Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity. J Mol Biol. 2002 Jan 18;315(3):339-50. [2]. Elgersma RC, et al. Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Kapurniotu A, et al. Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity. J Mol Biol. 2002 Jan 18;315(3):339-50.

[2]. Elgersma RC, et al. Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42.

Molecular Formula	C₄₃H₆₈N₁₂O₁₆
Molecular Weight	1009.07
Exact Mass	1008.49000
PSA	472.09000

Safety Phrases	22-24/25
WGK Germany	3

AMYLIN FRAGMENT 20-29 HUMAN

SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER

diabetes associated peptide fragment 20-29 human

SNNFGAILSS

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Amylin (20-29) (human)

Use of Amylin (20-29) (human)

Names

Amylin (20-29) (human) Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.