Tachyplesin I trifluoroacetate salt

Modify Date: 2024-01-10 08:10:40

Tachyplesin I trifluoroacetate salt Structure
Tachyplesin I trifluoroacetate salt structure
Common Name Tachyplesin I trifluoroacetate salt
CAS Number 118231-04-2 Molecular Weight 2263.74
Density N/A Boiling Point N/A
Molecular Formula C99H151N35O19S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tachyplesin I trifluoroacetate salt


Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1].

 Names

Name Tachyplesin
Synonym More Synonyms

 Tachyplesin I trifluoroacetate salt Biological Activity

Description Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1].
Related Catalog
References

[1]. D V Kuzmin, et al. In Vitro Study of Antitumor Effect of Antimicrobial Peptide Tachyplesin I in Combination with Cisplatin. Bull Exp Biol Med. 2018 Jun;165(2):220-224.  

 Chemical & Physical Properties

Molecular Formula C99H151N35O19S4
Molecular Weight 2263.74
Exact Mass 2262.08000
PSA 1027.68000
LogP 7.49060
InChIKey ZJQFYZCNRTZAIM-PMXBASNASA-N
SMILES CCC(C)C1NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C2CSSCC(NC1=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CCCNC(=N)N)C(N)=O)CSSCC(NC(=O)C(Cc1c[nH]c3ccccc13)NC(=O)C(N)CCCCN)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)C)C(=O)N2

 Synonyms

KWCFRVCYRGICYRRCR-NH2
tachyplesin peptide,Tachypleus tridentatus
Lipopolysaccharide-binding peptide
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