Tiopronin-d3

Modify Date: 2024-04-08 11:45:51

Tiopronin-d3 structure	Common Name	Tiopronin-d3
	CAS Number	1189700-74-0	Molecular Weight	166.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅H₆D₃NO₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tiopronin-d3

Tiopronin-d3 is the deuterium labeled Tiopronin. Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders[1][2].

Name	Tiopronin-d3

Description	Tiopronin-d3 is the deuterium labeled Tiopronin. Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Pu Zhang, et al. Detection of tiopronin in body fluids and pharmaceutical products using red-emissive DNA-stabilized silver nanoclusters as a fluorescent probe. Mikrochim Acta. 2019 Aug 8;186(9):609. [3]. Soohwan Yum, et al. N-(2-Mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant. Biochem Biophys Res Commun. 2014 Jan 17;443(3):1008-13.

Molecular Formula	C₅H₆D₃NO₃S
Molecular Weight	166.21

Tiopronin-d3

Use of Tiopronin-d3

Names

Tiopronin-d3 Biological Activity

Chemical & Physical Properties