Efloxate

Modify Date: 2025-09-18 15:19:44

Efloxate Structure
Efloxate structure
Common Name Efloxate
CAS Number 119-41-5 Molecular Weight 324.32700
Density 1.265g/cm3 Boiling Point 486.5ºC at 760 mmHg
Molecular Formula C19H16O5 Melting Point 123-124°
MSDS N/A Flash Point 269.1ºC

 Use of Efloxate


Efloxate is a vasodilator, used to treat chronic coronary insufficiency and Angina pectoris,

 Names

Name ethyl 2-(4-oxo-2-phenylchromen-7-yl)oxyacetate
Synonym More Synonyms

 Efloxate Biological Activity

Description Efloxate is a vasodilator, used to treat chronic coronary insufficiency and Angina pectoris,
Related Catalog

 Chemical & Physical Properties

Density 1.265g/cm3
Boiling Point 486.5ºC at 760 mmHg
Melting Point 123-124°
Molecular Formula C19H16O5
Molecular Weight 324.32700
Flash Point 269.1ºC
Exact Mass 324.10000
PSA 65.74000
LogP 3.40190
Vapour Pressure 1.28E-09mmHg at 25°C
Index of Refraction 1.59
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ1460000
CHEMICAL NAME :
Acetic acid, ((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)-, ethyl ester
CAS REGISTRY NUMBER :
119-41-5
BEILSTEIN REFERENCE NO. :
0313027
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H16-O5
MOLECULAR WEIGHT :
324.35
WISWESSER LINE NOTATION :
T66 BO EVJ CR& IO1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,561,1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,125,1982

 Safety Information

HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 EfloxateBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Secondary assay to identify inhibitors of non-replicating M. tb using luciferase expr...
Source: Broad Institute
Target: N/A
External Id: 2157-04_Inhibitor_Dose_DryPowder_Activity_Set4
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosi...
Source: Broad Institute
Target: N/A
External Id: 2157-01_Inhibitor_Dose_DryPowder_Activity
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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 Synonyms

Corosanin
Efloxatum
Recordil
Oxyflavil
[(4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy]-acetic acid,ethyl ester
(4-Oxo-2-phenyl-4H-chromen-7-yloxy)-essigsaeure-aethylester
Coril
EINECS 204-321-9
Efloxate
(4-oxo-2-phenyl-4H-chromen-7-yloxy)-acetic acid ethyl ester
Angorlisin
Oxiflavil
Flacethyle
7-ethoxycarbonylmethoxyflavone
Domucor
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