Xanthopterin
Xanthopterin structure
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Common Name | Xanthopterin | ||
|---|---|---|---|---|
| CAS Number | 119-44-8 | Molecular Weight | 179.136 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 686.5ºC at 760mmHg | |
| Molecular Formula | C6H5N5O2 | Melting Point | 410ºC | |
| MSDS | N/A | Flash Point | 369ºC | |
Use of XanthopterinXanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat[1].Xanthopterin inhibits RNA synthesis[4]. |
Summary: Xanthopterin, Chinese name: Xanthopterin, CAS number: 119-44-8, molecular formula: C6H5N5O2, molecular weight: 179.136. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | xanthopterin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat[1].Xanthopterin inhibits RNA synthesis[4]. |
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| Related Catalog | |
| In Vitro | Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC50=109 mM)[2]. Cell Viability Assay[2] Cell Line: MCF-7 cells Concentration: 7.8 mM-250 mM Incubation Time: 24 hours Result: Resulted in reduction in mitochondrial activity. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 2.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 686.5ºC at 760mmHg |
| Melting Point | 410ºC |
| Molecular Formula | C6H5N5O2 |
| Molecular Weight | 179.136 |
| Flash Point | 369ºC |
| Exact Mass | 179.044327 |
| PSA | 117.52000 |
| LogP | -3.90 |
| Index of Refraction | 1.992 |
| Storage condition | 2-8°C |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~82%
Xanthopterin CAS#:119-44-8 |
| Literature: Mohr; Kazimierczuk; Pfleiderer Helvetica Chimica Acta, 1992 , vol. 75, # 7 p. 2317 - 2326 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Journal of Applied Chemistry, , vol. 2, p. 591 Journal of the American Chemical Society, , vol. 71, p. 471 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Helvetica Chimica Acta, , vol. 75, # 7 p. 2317 - 2326 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Journal of Applied Chemistry, , vol. 2, p. 591 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Chemische Berichte, , vol. 89, p. 2400,2403 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Journal of the American Chemical Society, , vol. 75, p. 4450 |
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Xanthopterin CAS#:119-44-8 |
| Literature: Helvetica Chimica Acta, , vol. 75, # 7 p. 2317 - 2326 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 4 | |
CAS#:645-93-2
CAS#:56-40-6
CAS#:6538-79-0This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
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Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
|
|
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
|
|
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
|
|
Name: Spectrum HTS for Inhibitors of Aerobactin Synthetase IucA
Source: 23265
Target: IucA Synthetase from hypervirulent Klebsiella pneumoniae hvKP1
External Id: IucA Pilot Assay Spectrum Library
|
|
Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491
|
|
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
|
|
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary ...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2Venus
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|
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
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|
Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-aminopteridine-4(3H),6(5H)-dione |
| 4,6-Pteridinedione,2-amino-1,5-dihydro-(9CI) |
| Xanthopterin |
| 2-amino-3,5-dihydro-pteridine-4,6-dione |
| 2-amino-1,5-dihydropteridine-4,6-quinone |
| Uropterin |
| 2-amino-3,5-dihydropteridine-4,6-dione |
| 2-AMINO-1,5-DIHYDROPTERIDINE-4,6-DIONE |
| 4-Hydroxy-2-imino-1,5-dihydro-6(2H)-pteridinone |
| EINECS 204-325-0 |
| 2-Amino-3,5-dihydro-pteridin-4,6-dion |
| 2-Amino-1,5-dihydro-4,6-pteridinedione |
| 6-Hydroxy-2-imino-2,3-dihydropteridin-4(1H)-one |
| 2-Amino-4-oxo-6-hydroxy-3,4-dihydropteridine |
| 2-Aminopteridine-4,6-diol |
| 2-azanyl-1,5-dihydropteridine-4,6-dione |
| 2-AMINO-4,6-DIHYDROXYPTERIDENE |
| 2-Amino-4,6(1H,5H)-pteridinedione |
| MFCD00151242 |
| xanthopterine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of xanthopterin? |
| A: Polar surface area (PSA) of xanthopterin is 117.52000. |
| Q: What are the upstream materials of xanthopterin? |
| A: Related upstream materials(CAS) of xanthopterin: 146196-27-2;1131-35-7;492-11-5;49653-17-0;2757-91-7. |
| Q: What is the molecular weight of xanthopterin? |
| A: Molecular weight of xanthopterin is 179.136. |
| Q: What is the molecular formula of xanthopterin? |
| A: Molecular formula of xanthopterin is C6H5N5O2. |
| Q: What is the CAS number of xanthopterin? |
| A: CAS number of xanthopterin is 119-44-8. |
| Q: What are the downstream products of xanthopterin? |
| A: Related downstream products(CAS) of xanthopterin: 492-11-5;645-93-2;56-40-6;6538-79-0. |
| Q: What is the safety information for xanthopterin? |
| A: Safety information for xanthopterin: 26-37/39. |
| Q: What are the storage conditions for xanthopterin? |
| A: Storage conditions for xanthopterin: 2-8°C. |
| Q: What is the English name of xanthopterin? |
| A: The English name of xanthopterin is xanthopterin. |
| Q: What is the LogP of xanthopterin? |
| A: LogP of xanthopterin is -3.90. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |