6-Hydroxy Desloratadine

Modify Date: 2024-01-06 19:17:09

6-Hydroxy Desloratadine Structure
6-Hydroxy Desloratadine structure
 Common Name 6-Hydroxy Desloratadine
CAS Number 119410-05-8 Molecular Weight 326.82000
Density 1.3g/cm3 Boiling Point 520.3ºC at 760 mmHg
Molecular Formula C19H19ClN2O Melting Point N/A
MSDS N/A Flash Point 268.5ºC

 Names

Name 8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-6-ol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 520.3ºC at 760 mmHg
Molecular Formula C19H19ClN2O
Molecular Weight 326.82000
Flash Point 268.5ºC
Exact Mass 326.11900
PSA 45.15000
LogP 3.83860
Vapour Pressure 1.19E-11mmHg at 25°C
Index of Refraction 1.649

 Synthetic Route

8-Chloro-5,11-dihydro-11-(4-piperidinylidene)-6H-benzo(5,6)cyclohepta(1,2-b)pyridin-6-one structure

8-Chloro-5,11-d...

CAS#:119410-04-7

~84%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Schering Corporation Patent: US4804666 A1, 1989 ;
N/A structure

N/A

CAS#:119410-09-2

~59%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

N/A structure

N/A

CAS#:119410-11-6

Literature: Schering Corporation Patent: US5422351 A1, 1995 ;
Loratadine Impurity 2 structure

Loratadine Impu...

CAS#:31251-41-9

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
8-chloro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-one structure

8-chloro-11H-be...

CAS#:117811-16-2

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
8-Chloro-6-methoxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one structure

8-Chloro-6-meth...

CAS#:117811-22-0

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
N/A structure

N/A

CAS#:119410-11-6

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
N/A structure

N/A

CAS#:119410-09-2

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
Ethyl 4-[8-Chloro-6-[(ethoxycarbonyl)oxy]-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate structure

Ethyl 4-[8-Chlo...

CAS#:126063-19-2

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350
Ethyl 4-(8-Chloro-5,6-dihydro-6-oxo-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylate structure

Ethyl 4-(8-Chlo...

CAS#:126063-20-5

~%

6-Hydroxy Desloratadine Structure

6-Hydroxy Deslo...

CAS#:119410-05-8

Literature: Journal of Organic Chemistry, , vol. 55, # 10 p. 3341 - 3350

 Synonyms

6-OH desloratadine
6-Hydroxy Desloratadine
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Related Compounds: More...
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