Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

Modify Date: 2024-01-09 19:59:41

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure
Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate structure
Common Name Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
CAS Number 1198408-35-3 Molecular Weight 277.362
Density 1.1±0.1 g/cm3 Boiling Point 422.8±45.0 °C at 760 mmHg
Molecular Formula C15H23N3O2 Melting Point N/A
MSDS N/A Flash Point 209.5±28.7 °C

 Names

Name tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 422.8±45.0 °C at 760 mmHg
Molecular Formula C15H23N3O2
Molecular Weight 277.362
Flash Point 209.5±28.7 °C
Exact Mass 277.179016
PSA 69.18000
LogP 2.00
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.553

 Safety Information

HS Code 2933990090

 Synthetic Route

~99%

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure

Tert-butyl 4-(6...

CAS#:1198408-35-3

Literature: F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D. Patent: WO2013/24078 A1, 2013 ; Location in patent: Page/Page column 57; 58 ;

~58%

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure

Tert-butyl 4-(6...

CAS#:1198408-35-3

Literature: Cho, Young Shin; Borland, Maria; Brain, Christopher; Chen, Christine H.-T.; Cheng, Hong; Chopra, Rajiv; Chung, Kristy; Groarke, James; He, Guo; Hou, Ying; Kim, Sunkyu; Kovats, Steven; Lu, Yipin; O'Reilly, Marc; Shen, Junqing; Smith, Troy; Trakshel, Gary; Voegtle, Markus; Xu, Mei; Xu, Ming; Sung, Moo Je Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7938 - 7957

~%

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure

Tert-butyl 4-(6...

CAS#:1198408-35-3

Literature: F. HOFFMANN-LA ROCHE AG; BROTHERTON-PLEISS, Christine; JAIME-FIGUEROA, Saul; LOPEZ-TAPIA, Francisco Javier; LOU, Yan; OWENS, Timothy D. Patent: WO2013/24078 A1, 2013 ;

~%

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure

Tert-butyl 4-(6...

CAS#:1198408-35-3

Literature: Hoffmann-La Roche Inc.; Brotherton-Pleiss, Christine E.; Lopez-Tapia, Francisco Javier; Lou, Yan Patent: US2013/150360 A1, 2013 ;

~%

Tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Structure

Tert-butyl 4-(6...

CAS#:1198408-35-3

Literature: Cho, Young Shin; Borland, Maria; Brain, Christopher; Chen, Christine H.-T.; Cheng, Hong; Chopra, Rajiv; Chung, Kristy; Groarke, James; He, Guo; Hou, Ying; Kim, Sunkyu; Kovats, Steven; Lu, Yipin; O'Reilly, Marc; Shen, Junqing; Smith, Troy; Trakshel, Gary; Voegtle, Markus; Xu, Mei; Xu, Ming; Sung, Moo Je Journal of Medicinal Chemistry, 2010 , vol. 53, # 22 p. 7938 - 7957

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6-amino-3',4',5',6'-tetrahydro-2'H-3,4'-bipyridinyl-1'-carboxylic acid tert-butyl ester
1-piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester
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