2-Imidazolidinone

Modify Date: 2025-08-22 18:02:32

2-Imidazolidinone Structure
2-Imidazolidinone structure
Common Name 2-Imidazolidinone
CAS Number 120-93-4 Molecular Weight 86.092
Density 1.1±0.1 g/cm3 Boiling Point 358.7±11.0 °C at 760 mmHg
Molecular Formula C3H6N2O Melting Point 129-132 °C(lit.)
MSDS USA Flash Point 202.5±19.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name imidazolidin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 358.7±11.0 °C at 760 mmHg
Melting Point 129-132 °C(lit.)
Molecular Formula C3H6N2O
Molecular Weight 86.092
Flash Point 202.5±19.4 °C
Exact Mass 86.048012
PSA 41.13000
LogP -1.23
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.447
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ0570000
CHEMICAL NAME :
2-Imidazolidinone
CAS REGISTRY NUMBER :
120-93-4
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C3-H6-N2-O
MOLECULAR WEIGHT :
86.11
WISWESSER LINE NOTATION :
T5MVMTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,235,1982 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1000 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Blood - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB223-159 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
15 mg/kg
SEX/DURATION :
male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
REFERENCE :
85GUAJ "Antifertility Compounds in the Male and Female," Jackson, H., Springfield, IL, Charles C. Thomas, 1966 Volume(issue)/page/year: -,37,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83666 No. of Facilities: 159 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 4032 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83666 No. of Facilities: 76 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 6452 (estimated) No. of Female Employees: 347 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS NJ0570000
HS Code 2933290090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles17

More Articles
Computational thermochemistry of six ureas, imidazolidin-2-one, N,N'-trimethyleneurea, benzimidazolinone, parabanic acid, barbital (5,5'-diethylbarbituric acid), and 3,4,4'-trichlorocarbanilide, with an extension to related compounds.

J. Phys. Chem. A 114(34) , 9237-45, (2010)

A computational study of the structural and thermochemical properties of N-phenyl (open) and N-alkyl (cyclic) ureas, through the use of M05-2X and B3LYP density functional theory calculations has been...

Synthesis of new unsymmetrical 4,5-dihydroxy-2-imidazolidinones. Dynamic NMR spectroscopic study of the prototropic tautomerism in 1-(2-benzimidazolyl)-3-phenyl-4,5-dihydroxy-2-imidazolidinone.

Molecules 11(10) , 768-75, (2006)

The acid-catalyzed cyclocondensation in refluxing acetonitrile of aqueous glyoxal with N-heteroaryl-N'-phenylureas 4a-f (heteroaryl = 2-thiazolyl, 2-pyrimidinyl,2-pyrazinyl, 2-pyridinyl, 3-pyridinyl a...

[Preliminary pharmacological evaluation of new imidazolidinone-2, ethylenediamine and imidazoline derivatives].

Acta Pol. Pharm. 41(4) , 495-504, (1984)

 Synonyms

imidazolidin-2-one
2-Imidazolidinone
EINECS 204-436-4
Imidazolidone
Ethylenurea
Ethyleneurea
1,3-(ethane-1,2-diyl)urea
N,N'-ethyleneurea
ethylene urea
urea,ethylene
SD 6073
Imidazolidinone
2-Imidazolidone
N,N-Ethylenurea
2-Oxoimidazolidine
Imidazolid-2-one
MFCD00005257
oxoimidazolidine
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