(2R,3R)-BOC-dolaproine

Modify Date: 2025-08-26 21:58:11

(2R,3R)-BOC-dolaproine structure	Common Name	(2R,3R)-BOC-dolaproine
	CAS Number	120205-50-7	Molecular Weight	287.352
	Density	1.1±0.1 g/cm3	Boiling Point	397.8±17.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₂₅NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	194.4±20.9 °C

Use of (2R,3R)-BOC-dolaproine

N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].

Name	(2R,3R)-3-((S)-1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid
Synonym	More Synonyms

Description	N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

Density	1.1±0.1 g/cm3
Boiling Point	397.8±17.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₅NO₅
Molecular Weight	287.352
Flash Point	194.4±20.9 °C
Exact Mass	287.173279
PSA	76.07000
LogP	1.36
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.490

Precursor 7
CAS#:74-88-4 methyl iodide CAS#:69610-41-9 Boc-L- Prolinal CAS#:133164-07-5 [2S-[2R[(R),α... CAS#:135383-59-4 ethyl (2R,3R,4S...
CAS#:179039-97-5 methyl (2R,3R,2... CAS#:120205-60-9 (S)-tert-butyl ... CAS#:120205-61-0 (S)-tert-butyl ...
DownStream 0

(2R,3R)-3-Methoxy-2-methyl-3-[(2S)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-pyrrolidinyl]propanoic acid

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-

(2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-2-yl]propanoic acid

((2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (2R,3R)-BOC-dolaproine
Price: Check
Purity: 95.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: (2R,3R)-BOC-dolaproine
Price: ￥1976.0/250mg ￥1236.0/100mg ￥4966.0/1g
Purity: 95.0%
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Contact: Liu jia
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (2R,3R)-3-((S)-1-(TERT-BUTOXYCARBONYL)PYRROLIDIN-2-YL)-3-METHOXY-2-METHYLPROPANOIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥950/100mg

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(2R,3R)-BOC-dolaproine

Use of (2R,3R)-BOC-dolaproine

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(2R,3R)-BOC-dolaproine Biological Activity

Chemical & Physical Properties

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Precursor & DownStream

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