1β-Hydroxyeuscaphic acid

Modify Date: 2026-07-01 10:43:13

1β-Hydroxyeuscaphic acid Structure
1β-Hydroxyeuscaphic acid structure
Common Name 1β-Hydroxyeuscaphic acid
CAS Number 120211-98-5 Molecular Weight 518.73
Density 1.2±0.1 g/cm3 Boiling Point 619.1±55.0 °C at 760 mmHg
Molecular Formula C31H50O6 Melting Point N/A
MSDS N/A Flash Point 342.2±28.0 °C

 Use of 1β-Hydroxyeuscaphic acid


1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis[1].

 Names

Name (1R,2R,4aS,6aS,6bR,8aS,10S,11S,12S,12aR,12bS,14bS)-1,10,11,12-tetrahydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
Synonym More Synonyms

 1β-Hydroxyeuscaphic acid Biological Activity

Description 1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis[1].
Related Catalog
References

[1]. Hu J, et al. Hepatoprotection of 1β-hydroxyeuscaphic acid - the major constituent from Rubus aleaefolius against CCl4-induced injury in hepatocytes cells. Pharm Biol. 2013;51(6):686-690.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 619.1±55.0 °C at 760 mmHg
Molecular Formula C31H50O6
Molecular Weight 518.73
Flash Point 342.2±28.0 °C
Exact Mass 504.345093
PSA 118.22000
LogP 5.27
Vapour Pressure 0.0±4.1 mmHg at 25°C
Index of Refraction 1.591
InChIKey VULLSLYDWNGNKZ-HMBKWFJRSA-N
SMILES CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)C(O)C(O)C(O)C(C)(C)C5CCC43C)C2C1(C)O

 Safety Information

Hazard Codes Xi

 1β-Hydroxyeuscaphic acidBioassay

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Name: Hepatoprotective activity against CCl4-induced liver injury mouse model assessed as i...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5263920
Name: Hepatoprotective activity against CCl4-induced liver injury mouse model assessed as r...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5263919
Name: Cytotoxicity against mock-infected human H9 cells after 4 days
Source: ChEMBL
Target: H9
External Id: CHEMBL1004249
Name: Hepatoprotective activity against CCl4-induced liver injury mouse model assessed as r...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5263918
Name: Therapeutic index, ratio of IC50 for human H9 cells to EC50 for HIV1 3B
Source: ChEMBL
Target: N/A
External Id: CHEMBL1004250
Name: Antiviral activity against HIV1 3B in human H9 cells after 4 days by p24 antigen ELIS...
Source: ChEMBL
Target: Human immunodeficiency virus 1
External Id: CHEMBL1004248
Name: Hepatoprotective activity against CCl4-induced liver injury mouse model assessed as r...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL5263866
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 Synonyms

(1β,2α,3α)-1,2,3,19-Tetrahydroxyurs-12-en-28-oic acid
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