VGSCs-IN-1
Modify Date: 2023-01-18 09:37:32
VGSCs-IN-1 structure
|
Common Name | VGSCs-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1204296-79-6 | Molecular Weight | 303.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H12F3N3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VGSCs-IN-1VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research[1]. |
| Name | 2-(piperazin-1-yl)-6-(trifluoromethoxy)benzothiazole |
|---|
| Description | VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research[1]. |
|---|---|
| Related Catalog | |
| Target |
hNav1.4 hNav1.7 |
| References |
| Molecular Formula | C12H12F3N3OS |
|---|---|
| Molecular Weight | 303.30 |
| Exact Mass | 303.06500 |
| PSA | 65.63000 |
| LogP | 2.99830 |