Verlukast
Verlukast structure
|
Common Name | Verlukast | ||
|---|---|---|---|---|
| CAS Number | 120443-16-5 | Molecular Weight | 515.087 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 712.3±60.0 °C at 760 mmHg | |
| Molecular Formula | C26H27ClN2O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 384.6±32.9 °C | |
Use of VerlukastVerlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1]. |
| Name | 3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-[3-(dimethylamino)-3-oxopropyl]sulfanylmethyl]sulfanylpropanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1]. |
|---|---|
| Related Catalog | |
| Target |
leukotriene receptor[1] |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 712.3±60.0 °C at 760 mmHg |
| Molecular Formula | C26H27ClN2O3S2 |
| Molecular Weight | 515.087 |
| Flash Point | 384.6±32.9 °C |
| Exact Mass | 514.115173 |
| PSA | 121.10000 |
| LogP | 5.93 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.687 |
| InChIKey | AXUZQJFHDNNPFG-LHAVAQOQSA-N |
| SMILES | CN(C)C(=O)CCSC(SCCC(=O)O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 |
|
~82%
Verlukast CAS#:120443-16-5 |
| Literature: Hughes; Bergan; Amato; Reider; Grabowski Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 1787 - 1788 |
|
~%
Verlukast CAS#:120443-16-5 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 32, # 1 p. 127 - 130 |
|
~51%
Verlukast CAS#:120443-16-5 |
| Literature: Shinkai, I; Bhupathy, M Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 1 p. 127 - 130 |
|
~%
Verlukast CAS#:120443-16-5 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 26 p. 6252 - 6259 |
|
~%
Verlukast CAS#:120443-16-5 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 26 p. 6252 - 6259 |
|
~%
Verlukast CAS#:120443-16-5 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 26 p. 6252 - 6259 |
![3,3'-[[[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]methylene]bis(thio)]bis-propanoic Acid 1,1'-Dimethyl Ester structure](https://image.chemsrc.com/caspic/496/120385-96-8.png)
| 3-{[(R)-{3-[(E)-2-(7-Chloroquinolin-2-yl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| Propanoic acid, 3-[[(R)-[3-[(E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]- |
| MK 679 |
| 3-(((aR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-a-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic Acid |
| 3-{[(R)-{3-[(E)-2-(7-Chloro-2-quinolinyl)vinyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| Verlukastum |
| (R-(E))-3-(((3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoic Acid |
| 3-(((αR)-m-((E)-2-(7-Chloro-2-quinolyl)vinyl)-α-((2-(dimethylcarbamoyl)ethyl)thio)benzyl)thio)propionic acid |
| 3-{[(R)-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}{[3-(dimethylamino)-3-oxopropyl]sulfanyl}methyl]sulfanyl}propanoic acid |
| MK-0679 |
| VERLUKAST |