4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan

Modify Date: 2024-01-03 09:55:56

4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan Structure
4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan structure
Common Name 4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan
CAS Number 1206464-65-4 Molecular Weight 374.43
Density 1.3±0.1 g/cm3 Boiling Point 545.4±50.0 °C at 760 mmHg
Molecular Formula C21H26O6 Melting Point N/A
MSDS N/A Flash Point 283.7±30.1 °C

 Use of 4,4'-Dihydroxy-3,3',9-triMethoxy-9,9'-epoxylignan


4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC50s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively[1].

 Names

Name 4,4'-(((2S,3S,4S)-2-methoxytetrahydrofuran-3,4-diyl)bis(methylene))bis(2-methoxyphenol)
Synonym More Synonyms

  Biological Activity

Description 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC50s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively[1].
Related Catalog
References

[1]. Li H, et al. Cytotoxic lignans from Viburnum foetidum. Arch Pharm Res. 2013 Oct;36(10):1211-4.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 545.4±50.0 °C at 760 mmHg
Molecular Formula C21H26O6
Molecular Weight 374.43
Flash Point 283.7±30.1 °C
Exact Mass 374.172943
PSA 77.38000
LogP 2.08
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.594

 Safety Information

Hazard Codes Xi

 Synonyms

4,4'-{[(2S,3S,4S)-2-Methoxytetrahydrofuran-3,4-diyl]bis(methylene)}bis(2-methoxyphenol)
Phenol, 4,4'-[[(2S,3S,4S)-tetrahydro-2-methoxy-3,4-furandiyl]bis(methylene)]bis[2-methoxy-