physalin O

Modify Date: 2025-11-24 21:56:41

physalin O Structure
physalin O structure
Common Name physalin O
CAS Number 120849-18-5 Molecular Weight 528.54800
Density N/A Boiling Point N/A
Molecular Formula C28H32O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of physalin O


Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities[1][2].

 Names

Name physalin O

 physalin O Biological Activity

Description Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities[1][2].
Related Catalog
References

[1]. Kuo PC, et al. Physanolide A, a novel skeleton steroid, and other cytotoxic principles from Physalis angulata. Org Lett. 2006 Jul 6;8(14):2953-6.  

[2]. Ji L, et al. Physalins with anti-inflammatory activity are present in Physalis alkekengi var. franchetii and can function as Michael reaction acceptors. Steroids. 2012 Apr;77(5):441-7.  

 Chemical & Physical Properties

Molecular Formula C28H32O10
Molecular Weight 528.54800
Exact Mass 528.20000
PSA 156.66000
LogP 0.50980
InChIKey QFAOFAWTSOFSQA-PGNTUMIFSA-N
SMILES CC1C(=O)OC2CC1(C)C1C(=O)C3(O)OC14C(O)(CCC1C3C(O)C=C3CC=CC(=O)C31C)C(=O)OC24C
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