Ac-rC Phosphoramidite

Modify Date: 2024-01-09 08:19:17

Ac-rC Phosphoramidite Structure
Ac-rC Phosphoramidite structure
 Common Name Ac-rC Phosphoramidite
CAS Number 121058-88-6 Molecular Weight 902.098
Density N/A Boiling Point N/A
Molecular Formula C47H64N5O9PSi Melting Point N/A
MSDS USA Flash Point N/A

 Use of Ac-rC Phosphoramidite


Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].

 Names

Name DMT-2′O-TBDMS-rC(ac) Phosphoramidite
Synonym More Synonyms

 Ac-rC Phosphoramidite Biological Activity

Description Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].
Related Catalog
References

[1]. Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.

 Chemical & Physical Properties

Molecular Formula C47H64N5O9PSi
Molecular Weight 902.098
Exact Mass 901.421082
PSA 169.22000
LogP 10.84

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

Ac-rC Phosphoramidite
4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-2(1H)-pyrimidinone
Ac-rCPhosphoramidite
2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-
N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-
N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine
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