121058-88-6

121058-88-6 structure

Name: Ac-rC Phosphoramidite
Chemical Name: DMT-2′O-TBDMS-rC(ac) Phosphoramidite
CAS Number: 121058-88-6
Molecular Formula: C₄₇H₆₄N₅O₉PSi
Molecular Weight: 902.098
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2018-06-11 17:10:40
Modify Date: 2025-08-21 12:55:07
Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].

Name	DMT-2′O-TBDMS-rC(ac) Phosphoramidite
Synonyms	Ac-rC Phosphoramidite 4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-2(1H)-pyrimidinone Ac-rCPhosphoramidite 2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]- N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]- N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine

Description	Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others
References	[1]. Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

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~65%

121058-88-6

Literature: Reddy, M. P.; Farooqui, Firdous; Hanna, Naeem B. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8929 - 8932

40615-36-9

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

121058-82-0

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

18162-48-6

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

3768-18-1

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

51432-41-8

121058-88-6

Literature: Tetrahedron Letters, , vol. 30, # 1 p. 71 - 74

65-46-3

121058-88-6

Literature: Tetrahedron Letters, , vol. 30, # 1 p. 71 - 74