121058-88-6

121058-88-6 structure

Name: Ac-rC Phosphoramidite
Chemical Name: DMT-2′O-TBDMS-rC(ac) Phosphoramidite
CAS Number: 121058-88-6
Molecular Formula: C₄₇H₆₄N₅O₉PSi
Molecular Weight: 902.098
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2018-06-11 17:10:40
Modify Date: 2026-07-14 12:28:40
Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].

Name	DMT-2′O-TBDMS-rC(ac) Phosphoramidite
Synonyms	DMT-2'-O-TBDMS-C(Ac)-CE Ac-rC Phosphoramidite, 10 mM in DMSO Ac-rCPhosphoramidite N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)cytidine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite 2’-OTBDMS-rC(N-Ac) CE Phosphoramidite 2TBDMS-rC(AC) Phosphoramidite DNA/RNA Synthesis,Ac rC Phosphoramidite,Inhibitor,Ac-rC Phosphoramidite,inhibit,AcrC Phosphoramidite 2'-O-TBDMS-C(Ac)-CE-Phosphoramidite 2’-OTBDMS-rC(Ac) Amidite 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine-3’-Cyanoethyl Phosphoramidite 2'-TBDMS -Ac-rC-CE-Phosphoramidite 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramidite 5'-DMT-2'-O-TBDMS- N4-Acetyl-Cytidine Phosphoramidite N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 5'-DMT-2'-TBDMS-rC(N-Ac) Phosphoramidite N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite 2’-TBDMS-rC(N-Ac) Phosphoramidite 2'-O-TBDMS-C(Az)-CE Phosphoramidite N4-Ac-5'-O-DMT-2'-O-TBDMS-C-CE (K.F.) REF DUPL: 2'-TBDMS-rC(N-ac) Phosphoramidite N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite 5'-ODMT-2'-OTBDMS-N-Ac Cytidine-3'-OCA Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] Ac-rC phosphoramidite monomer 5'-O-DMT-N4-Acetyl-2'-O-TBDMS cytidine 3'-CE phosphoramidite 4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-2(1H)-pyrimidinone 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldiMethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoraMidite N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimeth DMT-2’-O-TBDMS -C(Ac)-CE- phosphoramidaite 2’-OTBDMS-rC(N-Ac) phosphoramidite 5'-Dimethoxytrityl-N-acetyl-Cytidine,2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine 3'-CE phosphoramidite 2'-TBDMS-C C Phosphoramidite Impurity 1 2'-O-TBDMS-C(Ac) CE Phosphoramidite 5'-O-DMT-2'-TBDMS-rC(N-Ac)-3'-CEDPA (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(tert-butyldimethylsilyloxy)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite N4-Ac-5'-O-DMT-2'-O-TBDMS-C-CE 2'-TBDMS-rC(Ac)Phosphoramidite DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite RNA N-Ac C Amidite 5’-DMT-2’-TBDMS-rC(N-Ac)-CE Phosphoramidite (2S,3S,4S,5S)-5-(4-AcetaMido-2-oxopyriMidin-1(2H)-yl)-2-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-((tert-butyldiMethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoraMidite DMT-2'-0-TBDMS-rC(Ac) N4-Ac-2'-O-TBDMS-5'-O-DMT-C-3'-CE-Phosphoramidite DMT-2'-O-TBDMS-C(Ac)-CE-Phosphoramidite

Description	Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others
References	[1]. Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.

Molecular Formula	C₄₇H₆₄N₅O₉PSi
Molecular Weight	902.098
Exact Mass	901.421082
PSA	169.22000
LogP	10.84

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

124482-92-4

121058-85-3

~65%

121058-88-6

Literature: Reddy, M. P.; Farooqui, Firdous; Hanna, Naeem B. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8929 - 8932

40615-36-9

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

121058-82-0

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

18162-48-6

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

3768-18-1

121058-88-6

Literature: Tetrahedron Letters, , vol. 36, # 49 p. 8929 - 8932

51432-41-8

121058-88-6

Literature: Tetrahedron Letters, , vol. 30, # 1 p. 71 - 74

65-46-3

121058-88-6

Literature: Tetrahedron Letters, , vol. 30, # 1 p. 71 - 74

Precursor 6
121058-85-3 40615-36-9 121058-82-0 18162-48-6
3768-18-1 65-46-3
DownStream 1
121058-85-3

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