CFM 1571 hydrochloride
Modify Date: 2024-01-09 09:55:44
CFM 1571 hydrochloride structure
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Common Name | CFM 1571 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1215548-30-3 | Molecular Weight | 444.954 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H29ClN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CFM 1571 hydrochlorideCFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC50 and IC50 of 5.49 μM and 2.84 μM, respectively. Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). CFM 1571 (hydrochloride) (compound 32) has the potential for the research of cardiovascular and other diseases[1][2]. |
| Name | CFM 1571 hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | CFM 1571 hydrochloride is the stimulator of the nitric oxide receptor, soluble guanylate cyclase (sGC) with an EC50 and IC50 of 5.49 μM and 2.84 μM, respectively. Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme activated by nitric oxide (NO). CFM 1571 (hydrochloride) (compound 32) has the potential for the research of cardiovascular and other diseases[1][2]. |
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| Related Catalog | |
| Target |
sGC[1][2] |
| In Vivo | Assessment of Pharmacokinetics (PK) profile of CFM 1571 (hydrochloride) (compound 32) in rat[1] . compd Cmax (ng/mL) AUC (ng/h/mL) tmax (h) F (%) 32b 6.4 61.1 2.7 12 b: dosed at 5 mg/kg po. |
| References |
| Molecular Formula | C23H29ClN4O3 |
|---|---|
| Molecular Weight | 444.954 |
| Exact Mass | 444.192810 |
| Appearance of Characters | White crystalline solid |
| Storage condition | Store at -20°C |
| Water Solubility | Soluble in DMSO > 10 mM |
| 1-Benzyl-3-[3-(dimethylamino)propoxy]-N-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide hydrochloride (1:1) |