Homo Sildenafil-d5

Modify Date: 2024-01-11 19:39:07

Homo Sildenafil-d5 structure	Common Name	Homo Sildenafil-d5
	CAS Number	1216711-61-3	Molecular Weight	493.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₇D₅N₆O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Homo Sildenafil-d5

Homo Sildenafil-d5 is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor[1][2].

Name	Homo Sildenafil-d5

Description	Homo Sildenafil-d5 is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor[1][2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63.

Molecular Formula	C₂₃H₂₇D₅N₆O₄S
Molecular Weight	493.63