OX-14
Modify Date: 2024-09-05 02:27:31
OX-14 structure
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Common Name | OX-14 | ||
|---|---|---|---|---|
| CAS Number | 1219126-87-0 | Molecular Weight | 324.141 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H11FN2O6P2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OX-14OX-14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite; inhibits bone resorption, significantly prevents the formation of osteolytic lesions in JJN3-NSG murine model of myeloma-induced bone disease; a new, highly potent bisphosphonate with lower bone binding affinity than other clinically relevant bisphosphonates. |
| Name | OX-14 |
|---|
| Description | OX-14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite; inhibits bone resorption, significantly prevents the formation of osteolytic lesions in JJN3-NSG murine model of myeloma-induced bone disease; a new, highly potent bisphosphonate with lower bone binding affinity than other clinically relevant bisphosphonates. |
|---|---|
| References | References 1. Lawson MA, et al. J Bone Miner Res. 2017 Sep;32(9):1860-1869. View Related Products by Target Other Targets |
| Molecular Formula | C9H11FN2O6P2 |
|---|---|
| Molecular Weight | 324.141 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: OX-14
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: OX-14
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: OX-14
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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