Isonipecotic acid-d9

Modify Date: 2024-01-09 07:30:44

Isonipecotic acid-d9 structure	Common Name	Isonipecotic acid-d9
	CAS Number	1219798-43-2	Molecular Weight	138.21
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₂D₉NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Isonipecotic acid-d9

Isonipecotic acid-d9 is the deuterium labeled Isonipecotic acid[1]. Isonipecotic acid is a GABAA receptor partial agonist[2].

Name	Isonipecotic acid-d9

Description	Isonipecotic acid-d9 is the deuterium labeled Isonipecotic acid[1]. Isonipecotic acid is a GABAA receptor partial agonist[2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Krehan D, et al. Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective GABA(C) receptor antagonists. Neurochem Int. 2003 Jun;42(7):561-5. [3]. Falch E, et al. GABA-mimetic activity and effects on diazepam binding of aminosulphonic acids structurally related to piperidine-4-sulphonic acid. J Neurochem. 1985 Jan44(1):68-75.

Molecular Formula	C₆H₂D₉NO₂
Molecular Weight	138.21