Isobutylparaben-d4

Modify Date: 2024-01-12 12:00:50

Isobutylparaben-d4 Structure
Isobutylparaben-d4 structure
Common Name Isobutylparaben-d4
CAS Number 1219805-33-0 Molecular Weight 198.25
Density N/A Boiling Point N/A
Molecular Formula C11H10D4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Isobutylparaben-d4


Isobutylparaben-d4 is the deuterium labeled Isobutylparaben[1]. Isobutylparaben (Isobutyl 4-hydroxybenzoate) is a constitutive androstane receptor (CAR) activator. Isobutylparaben has a broad-spectrum antimicrobial activity and widely used in personal care products and cosmetics[2].

 Names

Name Isobutylparaben-d4

 Isobutylparaben-d4 Biological Activity

Description Isobutylparaben-d4 is the deuterium labeled Isobutylparaben[1]. Isobutylparaben (Isobutyl 4-hydroxybenzoate) is a constitutive androstane receptor (CAR) activator. Isobutylparaben has a broad-spectrum antimicrobial activity and widely used in personal care products and cosmetics[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Chieri Fujino, et al. Comparative Study of the Effect of 17 Parabens on PXR-, CAR- And PPARα-mediated Transcriptional Activation. Food Chem Toxicol. 2019 Nov;133:110792.  

[3]. Fei Meng, et al. Isobutylparaben Negatively Affects Porcine Oocyte Maturation Through Increasing Oxidative Stress and Cytoskeletal Abnormalities. Environ Mol Mutagen. 2020 Apr61(4):433-444.  

 Chemical & Physical Properties

Molecular Formula C11H10D4O3
Molecular Weight 198.25