4-Nitrosomorpholine

Modify Date: 2024-01-14 17:25:06

4-Nitrosomorpholine Structure
4-Nitrosomorpholine structure
Common Name 4-Nitrosomorpholine
CAS Number 1219805-76-1 Molecular Weight 124.17
Density 1.3±0.1 g/cm3 Boiling Point 226.1±15.0 °C at 760 mmHg
Molecular Formula C4D8N2O2 Melting Point N/A
MSDS N/A Flash Point 90.5±20.4 °C

 Use of 4-Nitrosomorpholine


N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].

 Names

Name N-nitrosomorpholine-d8
Synonym More Synonyms

 4-Nitrosomorpholine Biological Activity

Description N-Nitrosomorpholine-d8 is deuterium labeled N-Nitrosomorpholine. N-Nitrosomorpholine is a nitrosamine that is sensitive to light. N-nitrosomorpholine is a strong animal carcinogen[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. K D Brunnemann, et al. N-Nitrosomorpholine and Other Volatile N-nitrosamines in Snuff Tobacco. Carcinogenesis. 1982;3(6):693-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 226.1±15.0 °C at 760 mmHg
Molecular Formula C4D8N2O2
Molecular Weight 124.17
Flash Point 90.5±20.4 °C
Exact Mass 116.058578
PSA 41.90000
LogP -0.55
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.547

 Synonyms

4-Nitrosomorpholine
N-NITROSOMORPHOLINE
n-nitrosomorpholine-d8
Morpholine, 4-nitroso-