Eglin c (41-49)

Modify Date: 2024-01-03 20:08:49

Eglin c (41-49) Structure
Eglin c (41-49) structure
Common Name Eglin c (41-49)
CAS Number 122299-11-0 Molecular Weight 1063.20000
Density 1.44 g/cm3 Boiling Point N/A
Molecular Formula C48H78N12O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Eglin c (41-49)


Eglin c (41-49) is a peptide fragment related to eglin c. Eglin c (41-49) shows inhibitory effects to cathepsin G and α-chymotrypsin with Ki values of 42 and 20 μM, respectively[1].

 Names

Name (3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methyl-2-[[
Synonym More Synonyms

 Eglin c (41-49) Biological Activity

Description Eglin c (41-49) is a peptide fragment related to eglin c. Eglin c (41-49) shows inhibitory effects to cathepsin G and α-chymotrypsin with Ki values of 42 and 20 μM, respectively[1].
Related Catalog
References

[1]. Okada Y, et al. Synthesis of peptide fragments related to eglin c and examination of their inhibitory effect on human leukocyte elastase, cathepsin G and alpha-chymotrypsin. Biochem Biophys Res Commun. 1989 May 30;161(1):272-5.  

 Chemical & Physical Properties

Density 1.44 g/cm3
Molecular Formula C48H78N12O15
Molecular Weight 1063.20000
Exact Mass 1062.57000
PSA 469.94000
LogP 4.75110
Index of Refraction 1.635

 Synthetic Route

~81%

Eglin c (41-49) Structure

Eglin c (41-49)

CAS#:122299-11-0

Literature: Tsuboi; Takeda; Okada; Nagamatsu; Yamamoto Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 184 - 186

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(3S)-4-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,3-dihydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]butanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid
Eglin c (41-49)
H-Ser-Pro-Val-Thr-Leu-Asp-Leu-Arg-Tyr-OH
Ser-pro-val-thr-leu-asp-leu-arg-tyr-OH