QL-IX-55

Modify Date: 2024-01-16 01:13:58

QL-IX-55 Structure
QL-IX-55 structure
Common Name QL-IX-55
CAS Number 1223002-54-7 Molecular Weight 450.39
Density N/A Boiling Point N/A
Molecular Formula C24H14F4N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of QL-IX-55


QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.

 Names

Name 9-(6-aminopyridin-3-yl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one
Synonym More Synonyms

 QL-IX-55 Biological Activity

Description QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.
Related Catalog
References

[1]. Liu Q, Ren T, Fresques T, Oppliger W, Niles BJ, Hur W, Sabatini DM, Hall MN, Powers T, Gray NS.Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae.ACS Chem Biol. 2012 Jun 15;7(6):982-7.

 Chemical & Physical Properties

Molecular Formula C24H14F4N4O
Molecular Weight 450.39
Exact Mass 450.11000
PSA 74.53000
LogP 5.27110

 Synonyms

QL-IX-55
CS-0703
9-(6-aminopyridin-3-yl)-1-(4-fluoro-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
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