AZD3839

Modify Date: 2024-02-04 09:58:50

AZD3839 structure	Common Name	AZD3839
	CAS Number	1227163-56-5	Molecular Weight	449.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₁₅F₄N₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AZD3839

(Rac)-AZD3839 is an orally active beta-amyloid precursor protein cleaving enzyme (BACE1) inhibitor that is blood-brain barrier-permeable. (Rac)-AZD3839 has an affinity for the human ether-a-go-go related gene (hERG) ion channel. (Rac)-AZD3839 can be used in the research of Alzheimer's disease[1].

Name	4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine
Synonym	More Synonyms

Description	(Rac)-AZD3839 is an orally active beta-amyloid precursor protein cleaving enzyme (BACE1) inhibitor that is blood-brain barrier-permeable. (Rac)-AZD3839 has an affinity for the human ether-a-go-go related gene (hERG) ion channel. (Rac)-AZD3839 can be used in the research of Alzheimer's disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Britt-Marie Swahn, et, al. Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides. J Med Chem2012, 55, 21.

Molecular Formula	C₂₄H₁₅F₄N₅
Molecular Weight	449.40
Exact Mass	449.12600
PSA	77.05000
LogP	4.84320
Storage condition	-20℃

4-Fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine

AZD3839

AZD3839

Use of AZD3839

Names

AZD3839 Biological Activity

Chemical & Physical Properties

Synonyms