2-Chloroacetamide-d4

Modify Date: 2024-01-12 14:54:38

2-Chloroacetamide-d4 Structure
2-Chloroacetamide-d4 structure
Common Name 2-Chloroacetamide-d4
CAS Number 122775-20-6 Molecular Weight 97.53690
Density N/A Boiling Point N/A
Molecular Formula C2ClD4NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Chloroacetamide-d4


2-Chloroacetamide-d4 is the deuterium labeled 2-Chloroacetamide[1]. 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase[2][3][4].

 Names

Name 2-chloro-N,N,2,2-tetradeuterioacetamide
Synonym More Synonyms

 2-Chloroacetamide-d4 Biological Activity

Description 2-Chloroacetamide-d4 is the deuterium labeled 2-Chloroacetamide[1]. 2-Chloroacetamide is a preservative and is a herbicide for both uplands and paddy fields. 2-Chloroacetamide is a biocide in agriculture, glues, paints and coatings. 2-Chloroacetamide inhibits very-long-chain fatty acid elongase[2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Hidenori Okamoto, et al. Synthesis and Herbicidal Activity of N(1-Arylethenyl)-2-chloroacetamides. Agricultural and Biological Chemistry, Volume 55, 1991-Issue 11.

[3]. A Fonia, et al. Active Sensitization to Chloracetamide. Contact Dermatitis. 2009 Jan60(1):58-9.  

[4]. Christian Eckermann, et al. Covalent Binding of Chloroacetamide Herbicides to the Active Site Cysteine of Plant Type III Polyketide Synthases. Phytochemistry. 2003 Nov64(6):1045-54.  

 Chemical & Physical Properties

Molecular Formula C2ClD4NO
Molecular Weight 97.53690
Exact Mass 97.02320
PSA 43.09000
LogP 0.41080

 Synonyms

|A-Chloroacetamide-d4
Chloracetamide-d4
Microcide-d4
Chloroacetamide-d4
2-Chloroacetamide-d4
2-Chloroacetamide-N,N,2,2-d4
KM 101-d4
Mergal AF-d4