C 21

Modify Date: 2024-02-15 12:24:21

C 21 structure	Common Name	C 21
	CAS Number	1229236-78-5	Molecular Weight	2166.92
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₉₀H₁₆₁ClN₃₆O₂₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of C 21

C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM. C21 inhibits PRMT6 with an IC50 of 8.8 μM[1].

Name	C 21
Synonym	More Synonyms

Description	C21 is a potent, irreversible, and selective PRMT1 inhibitor with an IC50 of 1.8 μM. C21 inhibits PRMT6 with an IC50 of 8.8 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	IC50: 1.8 μM (PRMT1); 8.8 μM (PRMT6)[1]
References	[1]. Obiamaka Obianyo, et al. A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation. Chembiochem. 2010 Jun 14;11(9):1219-23.

Density	1.5±0.1 g/cm3
Molecular Formula	C₉₀H₁₆₁ClN₃₆O₂₄
Molecular Weight	2166.92
Exact Mass	2165.217285
LogP	-11.97
Index of Refraction	1.653

N-Acetyl-L-serylglycyl-N5-(2-chloroethanimidoyl)-L-ornithylglycyl-L-lysylglycylglycyl-L-lysylglycyl-L-leucylglycyl-L-lysylglycylglycyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-arginyl-L-lysyl-L-valin e

L-Valine, N-acetyl-L-serylglycyl-N5-(2-chloro-1-iminoethyl)-L-ornithylglycyl-L-lysylglycylglycyl-L-lysylglycyl-L-leucylglycyl-L-lysylglycylglycyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-arginyl-L-ly 
syl-

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