Epetraborole hydrochloride

Modify Date: 2024-01-13 14:14:24

Epetraborole hydrochloride structure	Common Name	Epetraborole hydrochloride
	CAS Number	1234563-16-6	Molecular Weight	273.521
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₇BClNO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Epetraborole hydrochloride

Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of infections caused by Gram-negative bacteria. Epetraborole hydrochloride is a bacteriostatic compound that can against a wide range of anaerobic and Gram-negative bacteria, including multidrug-resistant pathogens, such as extended-spectrum-β-lactamase-, metallo-β-lactamase-, and carbapenemase-producing organism.

Name	(3S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)-2,1-benzoxaborol-1(3H)-ol hydrochloride (1:1)
Synonym	More Synonyms

Description	Epetraborole hydrochloride is a novel leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding "to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase". It is intended for the treatment of infections caused by Gram-negative bacteria. Epetraborole hydrochloride is a bacteriostatic compound that can against a wide range of anaerobic and Gram-negative bacteria, including multidrug-resistant pathogens, such as extended-spectrum-β-lactamase-, metallo-β-lactamase-, and carbapenemase-producing organism.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Infection
References	[1]. Goldstein EJ et al. Comparative in vitro activities of GSK2251052, a novel boron-containing leucyl-tRNA synthetase inhibitor, against 916 anaerobic organisms.Antimicrob Agents Chemother. 2013 May;57(5):2401-4. [2]. O'Dwyer K et al. Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment ofcomplicated urinary tract infections. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Infection

References

[1]. Goldstein EJ et al. Comparative in vitro activities of GSK2251052, a novel boron-containing leucyl-tRNA synthetase inhibitor, against 916 anaerobic organisms.Antimicrob Agents Chemother. 2013 May;57(5):2401-4.

[2]. O'Dwyer K et al. Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment ofcomplicated urinary tract infections. Antimicrob Agents Chemother. 2015 Jan;59(1):289-98.

Molecular Formula	C₁₁H₁₇BClNO₄
Molecular Weight	273.521
Exact Mass	273.093903
Storage condition	2-8℃

(3S)-3-(Aminomethyl)-7-(3-hydroxypropoxy)-2,1-benzoxaborol-1(3H)-ol hydrochloride (1:1)

1-Propanol, 3-[[(3S)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-, hydrochloride (1:1)

Epetraborole HCl

Epetraborole hydrochloride

AN3365

Epetraborole (hydrochloride)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Epetraborole(hydrochloride)
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: AN3365(Epetraborole)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: AN3365(Epetraborole)
Price: $550.0/100mg $1000.0/250mg $1900.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (S)-3-(aminomethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: $181/10mM*1mLinWater

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Epetraborole hydrochloride

Use of Epetraborole hydrochloride

Names

Epetraborole hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

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