3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile

Modify Date: 2024-02-05 18:05:08

3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile structure	Common Name	3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile
	CAS Number	123548-56-1	Molecular Weight	367.74100
	Density	1.43g/cm3	Boiling Point	588.3ºC at 760mmHg
	Molecular Formula	C₁₅H₁₄ClN₃O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	309.6ºC

Use of 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile

Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].

Name	[2-[3-[(2-acetyloxyacetyl)amino]-2-chloro-5-cyanoanilino]-2-oxoethyl] acetate
Synonym	More Synonyms

Description	Acreozast (TYB-2285) is a histamine release inhibitor. Acreozast inhibits the histamine release primed with IL-3. Acreozast might regulate allergic inflammation in vivo by the suppression of mediator release primed with IL-3[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Watanabe A, et al. Effect of TYB-2285 on antigen-induced histamine release from mouse bone marrow-derived persisting cells (P-cells) primed with interleukin-3-containing conditioned medium (IL3-CM). Gen Pharmacol. 1993 Sep;24(5):1207-11.

Density	1.43g/cm3
Boiling Point	588.3ºC at 760mmHg
Molecular Formula	C₁₅H₁₄ClN₃O₆
Molecular Weight	367.74100
Flash Point	309.6ºC
Exact Mass	367.05700
PSA	141.57000
LogP	2.51388
Vapour Pressure	8.03E-14mmHg at 25°C
Index of Refraction	1.571