DSPE-PEG-Folate

Modify Date: 2024-03-02 15:17:18

DSPE-PEG-Folate Structure
DSPE-PEG-Folate structure
Common Name DSPE-PEG-Folate
CAS Number 1236288-25-7 Molecular Weight 6226.47
Density N/A Boiling Point N/A
Molecular Formula C287H558N11O127P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSPE-PEG-Folate


DSPE-PEG-Folate (Mw 3350) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research[1][2][3].

 Names

Name 1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[folate(polyethylene glycol)-5000] (aMMoniuM salt)

 DSPE-PEG-Folate Biological Activity

Description DSPE-PEG-Folate (Mw 3350) is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research[1][2][3].
Related Catalog
References

[1]. Werner ME, et, al. Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis. Biomaterials. 2011 Nov;32(33):8548-54.  

[2]. Li Y, et, al. Self-Assembled Nanoparticles Based on Amphiphilic Anticancer Drug-Phospholipid Complex for Targeted Drug Delivery and Intracellular Dual-Controlled Release. ACS Appl Mater Interfaces. 2015 Aug 19;7(32):17573-81.  

[3]. Patlolla RR, et al. Folate-targeted etoposide-encapsulated lipid nanospheres. J Drug Target. 2008 May;16(4):269-75.  

 Chemical & Physical Properties

Molecular Formula C287H558N11O127P
Molecular Weight 6226.47

 Safety Information

Hazard Codes Xi
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