Escin IA
Escin IA structure
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Common Name | Escin IA | ||
|---|---|---|---|---|
| CAS Number | 123748-68-5 | Molecular Weight | 1131.257 | |
| Density | 1.46 | Boiling Point | 1140.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C55H86O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 311.8±27.8 °C | |
Use of Escin IAEscin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Escin IA |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.46 |
|---|---|
| Boiling Point | 1140.6±65.0 °C at 760 mmHg |
| Molecular Formula | C55H86O24 |
| Molecular Weight | 1131.257 |
| Flash Point | 311.8±27.8 °C |
| Exact Mass | 1130.550903 |
| PSA | 388.04000 |
| LogP | 1.88 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.628 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2E)-2-methyl-2-butenoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic 
 acid |
| (3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid |
| Aescin A |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the boiling point of Escin IA? |
| A: Boiling point of Escin IA is 1140.6±65.0 °C at 760 mmHg. |
| Q: What is the CAS number of Escin IA? |
| A: CAS number of Escin IA is 123748-68-5. |
| Q: What is the molecular weight of Escin IA? |
| A: Molecular weight of Escin IA is 1131.257. |
| Q: What is the English name of Escin IA? |
| A: The English name of Escin IA is Escin IA. |
| Q: What is the molecular formula of Escin IA? |
| A: Molecular formula of Escin IA is C55H86O24. |
| Q: What are the uses of Escin IA? |
| A: Main uses of Escin IA: Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression[1][2]. |
| Q: What is the LogP of Escin IA? |
| A: LogP of Escin IA is 1.88. |
| Q: What English synonyms does Escin IA have? |
| A: English synonyms of Escin IA: (3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2E)-2-methyl-2-butenoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid, (3β,16α,21β,22α)-22-Acetoxy-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid, Aescin A. |
| Q: What is the polar surface area (PSA) of Escin IA? |
| A: Polar surface area (PSA) of Escin IA is 388.04000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |