Tetra(hydroxymethyl)phosphonium chloride

Modify Date: 2025-08-21 12:43:56

Tetra(hydroxymethyl)phosphonium chloride Structure
Tetra(hydroxymethyl)phosphonium chloride structure
Common Name Tetra(hydroxymethyl)phosphonium chloride
CAS Number 124-64-1 Molecular Weight 190.562
Density 1.341 g/mL at 25 °C Boiling Point 115°C/760mmHg
Molecular Formula C4H12ClO4P Melting Point 154°C
MSDS N/A Flash Point > 96ºC

 Names

Name Tetrakis(hydroxymethyl)phosphonium chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.341 g/mL at 25 °C
Boiling Point 115°C/760mmHg
Melting Point 154°C
Molecular Formula C4H12ClO4P
Molecular Weight 190.562
Flash Point > 96ºC
Exact Mass 190.016174
PSA 94.51000
Index of Refraction n20/D 1.512
Water Solubility >=10 g/100 mL at 20 ºC

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TA2450000
CHEMICAL NAME :
Phosphonium, tetrakis(hydroxymethyl)-, chloride
CAS REGISTRY NUMBER :
124-64-1
LAST UPDATED :
199710
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C4-H12-O4-P.Cl
MOLECULAR WEIGHT :
190.58
WISWESSER LINE NOTATION :
Q1P1Q1Q1Q &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
161 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
3800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7200 mg/kg/90D-I
TOXIC EFFECTS :
Peripheral Nerve and Sensation - sensory syndrome diagnostic of central lesion Behavioral - muscle weakness

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
5000 ppm
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 6,259,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,95,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,95,1990 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 17,101,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0112 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 100 (estimated)

 Safety Information

Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R21;R25;R38;R41;R42/43;R51/53
Safety Phrases S22-S26-S36/37/39-S45-S60-S61
RIDADR UN 2810 6.1/PG 3
WGK Germany 3
RTECS TA2450000
Packaging Group III
Hazard Class 8
HS Code 2931900090

 Synthetic Route

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Tetra(hydroxymethyl)phosphonium chloride Structure

Tetra(hydroxyme...

CAS#:124-64-1

Literature: Journal of the American Chemical Society, , vol. 77, p. 3923 Collection of Czechoslovak Chemical Communications, , vol. 26, p. 2401 - 2409 Tr. Kazakhsk. Khim.-Tekhnol. Inst., , # 29 p. 20 - 21 C. A., , vol. 58, p. 547

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Tetra(hydroxymethyl)phosphonium chloride Structure

Tetra(hydroxyme...

CAS#:124-64-1

Literature: Journal of the American Chemical Society, , vol. 43, p. 1686

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Tetra(hydroxymethyl)phosphonium chloride Structure

Tetra(hydroxyme...

CAS#:124-64-1

Literature: Justus Liebigs Annalen der Chemie, , vol. 659, p. 49 - 63

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Tetra(hydroxymethyl)phosphonium chloride
EINECS 204-707-7
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1)
tetrakis(hydroxymethyl)phosphanium,chloride
MFCD00031687
Tetrakis(hydroxymethyl)phosphonium chloride
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