SPI-112Me
Modify Date: 2025-08-24 22:51:16
SPI-112Me structure
|
Common Name | SPI-112Me | ||
|---|---|---|---|---|
| CAS Number | 1243685-62-2 | Molecular Weight | 482.484 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C23H19FN4O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SPI-112MeSPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays. |
| Name | SPI-112Me |
|---|---|
| Synonym | More Synonyms |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H19FN4O5S |
| Molecular Weight | 482.484 |
| Exact Mass | 482.106018 |
| LogP | 3.86 |
| Index of Refraction | 1.667 |
| InChIKey | RRGWXUGPBJKXAI-UHFFFAOYSA-N |
| SMILES | COC(=O)c1cccc(N=Nc2c(O)[nH]c3ccc(S(=O)(=O)NCc4ccc(F)cc4)cc23)c1 |
| Storage condition | -20℃ |
| Benzoic acid, 3-[(2Z)-2-[5-[[[(4-fluorophenyl)methyl]amino]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazinyl]-, methyl ester |
| Methyl 3-[(2Z)-2-{5-[(4-fluorobenzyl)sulfamoyl]-2-oxo-1,2-dihydro-3H-indol-3-ylidene}hydrazino]benzoate |