Cholest-5-ene-3-thiol,(3b)-

Modify Date: 2024-01-12 03:18:51

Cholest-5-ene-3-thiol,(3b)- Structure
Cholest-5-ene-3-thiol,(3b)- structure
Common Name Cholest-5-ene-3-thiol,(3b)-
CAS Number 1249-81-6 Molecular Weight 402.71900
Density 0.98g/cm3 Boiling Point 482.4ºC at 760mmHg
Molecular Formula C27H46S Melting Point 97-99ºC(lit.)
MSDS Chinese USA Flash Point 224ºC

 Use of Cholest-5-ene-3-thiol,(3b)-


Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery[1][2].

 Names

Name Cholest-5-ene-3.β.-thiol
Synonym More Synonyms

 Cholest-5-ene-3-thiol,(3b)- Biological Activity

Description Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery[1][2].
Related Catalog
References

[1]. Huang Z, et al. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Mol Ther. 2005 Mar;11(3):409-17.  

[2]. Ya. A. Gromova, et al. Adsorption Properties of Hybrid Metal–Mesogenic Silver–Cholesterol and Silver–Thiocholesterol Nanosystems. PHYSICAL CHEMISTRY OF NANOCLUSTERS AND NANOMATERIALS. 2019.

 Chemical & Physical Properties

Density 0.98g/cm3
Boiling Point 482.4ºC at 760mmHg
Melting Point 97-99ºC(lit.)
Molecular Formula C27H46S
Molecular Weight 402.71900
Flash Point 224ºC
Exact Mass 402.33200
PSA 38.80000
LogP 8.32620
Vapour Pressure 5.38E-09mmHg at 25°C
Index of Refraction 1.53

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles13

More Articles
The hedgehog receptor patched is involved in cholesterol transport.

PLoS ONE 6 , e23834, (2011)

Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway act...

Poly(amidoamine) conjugates with disulfide-linked cholesterol pendants self-assembling into redox-sensitive nanoparticles.

Biomacromolecules 9(10) , 2693-704, (2008)

Poly(amidoamine) (PAA) networks that are obtained by the use of cystamine as a cross-linking agent in the reaction with 2,2'-dithiodipyridine turn into linear PAAs with dithiopyridyl side groups that ...

Effect of the nature of the spacer on gene transfer efficacies of novel thiocholesterol derived gemini lipids in different cell lines: a structure-activity investigation.

J. Med. Chem. 51(8) , 2533-40, (2008)

A structure-activity investigation was undertaken to see the effect of the nature of the spacer on the gene transfection efficacies of thiocholesterol-derived cationic gemini lipids possessing disulfi...

 Synonyms

EINECS 215-003-4
Cholest-5-ene-3b-thiol
3-thiocholesterol
MFCD00003647
5-CHOLESTEN-3ALPHA-THIOL
THIOCHOLESTEROL SEALED AMPULE
THIOCHOLESTEROL
Cholesteryl mercaptan
cholest-5-ene-3beta-thiol