polyphemusin I

Modify Date: 2025-08-27 14:25:02

polyphemusin I Structure
polyphemusin I structure
Common Name polyphemusin I
CAS Number 125139-67-5 Molecular Weight 2453.94
Density 1.54±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C108H161N39O20S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of polyphemusin I


Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges[1].

 Names

Name polyphemusin I

 polyphemusin I Biological Activity

Description Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges[1].
Related Catalog
References

[1]. Jon-Paul S Powers, et al. The antimicrobial peptide polyphemusin localizes to the cytoplasm of Escherichia coli following treatment. Antimicrob Agents Chemother. 2006 Apr;50(4):1522-4.  

 Chemical & Physical Properties

Density 1.54±0.1 g/cm3(Predicted)
Molecular Formula C108H161N39O20S4
Molecular Weight 2453.94
InChIKey KTOJPCYXPSDVQC-HLICZWCASA-N
SMILES CC(C)C1NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCNC(=N)N)NC(=O)C(N)CCCNC(=N)N)CSSCC(C(=O)NC(CCCNC(=N)N)C(N)=O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C2CSSCC(NC1=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)N2
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