Polyphemusin II-Derived Peptide

Modify Date: 2025-08-26 11:16:33

Polyphemusin II-Derived Peptide Structure
Polyphemusin II-Derived Peptide structure
Common Name Polyphemusin II-Derived Peptide
CAS Number 229030-20-0 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C90H141N33O18S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Polyphemusin II-Derived Peptide


Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4[1].

 Names

Name Polyphemusin II-Derived Peptide

 Polyphemusin II-Derived Peptide Biological Activity

Description Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4[1].
Related Catalog
References

[1]. H Tamamura, et al. A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140. Biochem Biophys Res Commun. 1998 Dec 30;253(3):877-82.  

 Chemical & Physical Properties

Molecular Formula C90H141N33O18S2
InChIKey IMOHHNXUCDZLKM-ADZSTZGASA-N
SMILES N=C(N)NCCCC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC1CSSCC(C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)C(CCCNC(N)=O)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C2CCCN2C(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc2ccc(O)cc2)NC1=O
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