L-156,602

Modify Date: 2024-01-29 13:15:14

L-156,602 Structure
L-156,602 structure
Common Name L-156,602
CAS Number 125228-51-5 Molecular Weight 840.96
Density N/A Boiling Point N/A
Molecular Formula C38H64N8O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-156,602


L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH)[1][2].

 Names

Name l-156,602

 L-156,602 Biological Activity

Description L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH)[1][2].
Related Catalog
Target

C5a receptor[1][2]

References

[1]. Tsuji RF, et al. Effects of L-156,602, a C5a receptor antagonist, on mouse experimental models of inflammation. Biosci Biotechnol Biochem. 1992 Dec;56(12):2034-6.  

[2]. Tsuji RF, et al. Anti-inflammatory effects and specificity of L-156,602: comparison of effects on concanavalin A and zymosan-induced footpad edema, and contact sensitivity response. Immunopharmacology. 1995 Feb;29(1):79-87.  

 Chemical & Physical Properties

Molecular Formula C38H64N8O13
Molecular Weight 840.96
Exact Mass 840.45900
PSA 279.95000
LogP 0.19240
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