Methyl-PEG9-bromide

Modify Date: 2024-01-09 19:44:23

Methyl-PEG9-bromide Structure
Methyl-PEG9-bromide structure
Common Name Methyl-PEG9-bromide
CAS Number 125562-30-3 Molecular Weight 491.412
Density 1.2±0.0 g/cm3 Boiling Point 498.1±0.0 °C at 760 mmHg
Molecular Formula C19H39BrO9 Melting Point N/A
MSDS N/A Flash Point 208.4±0.0 °C

 Use of Methyl-PEG9-bromide


m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG9-bromide
Synonym More Synonyms

 Methyl-PEG9-bromide Biological Activity

Description m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Density 1.2±0.0 g/cm3
Boiling Point 498.1±0.0 °C at 760 mmHg
Molecular Formula C19H39BrO9
Molecular Weight 491.412
Flash Point 208.4±0.0 °C
Exact Mass 490.177734
LogP -0.88
Vapour Pressure 0.0±0.0 mmHg at 25°C
Index of Refraction 1.462

 Synonyms

28-Bromo-2,5,8,11,14,17,20,23,26-nonaoxaoctacosane
2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane, 28-bromo-
MFCD28950767
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