Macitentan D4
Modify Date: 2024-01-10 04:51:36
Macitentan D4 structure
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Common Name | Macitentan D4 | ||
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| CAS Number | 1258428-05-5 | Molecular Weight | 592.29800 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 692.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C19H16D4Br2N6O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 372.5±34.3 °C | |
Use of Macitentan D4Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan is used for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1]. |
| Name | N-[5-(4-Bromophenyl)-6-({2-[(5-bromo-2-pyrimidinyl)oxy](2H4)ethyl}oxy)-4-pyrimidinyl]-N'-propylsulfuric diamide |
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| Synonym | More Synonyms |
| Description | Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan is used for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1]. |
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| Related Catalog | |
| Target |
ETA/ETB[1] |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 692.4±65.0 °C at 760 mmHg |
| Molecular Formula | C19H16D4Br2N6O4S |
| Molecular Weight | 592.29800 |
| Flash Point | 372.5±34.3 °C |
| Exact Mass | 589.98800 |
| PSA | 136.60000 |
| LogP | 5.41 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.634 |
| N-[5-(4-Bromophenyl)-6-({2-[(5-bromo-2-pyrimidinyl)oxy](H)ethyl}oxy)-4-pyrimidinyl]-N'-propylsulfuric diamide |
| Sulfamide, N-[5-(4-bromophenyl)-6-[[2-[(5-bromo-2-pyrimidinyl)oxy]ethyl-1,1,2,2-d]oxy]-4-pyrimidinyl]-N'-propyl- |