2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine

Modify Date: 2025-08-26 11:24:19

2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine structure	Common Name	2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine
	CAS Number	1260177-41-0	Molecular Weight	412.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₇ClN₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine

2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

Description	2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₆H₁₇ClN₄O₇
Molecular Weight	412.78
Exact Mass	412.07900
PSA	131.73000
LogP	0.80360

2-amino-9-(2,3,...

CAS#:107037-21-8

~87%

2-Chloro-9-[(2,...

CAS#:1260177-41-0

Literature: Gillerman, Irina; Fischer, Bilha Journal of Medicinal Chemistry, 2011 , vol. 54, # 1 p. 107 - 121

Precursor 1
CAS#:107037-21-8 2-amino-9-(2,3,...
DownStream 1
CAS#:5466-11-5 2-Chloro-9-(bet...

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2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine

Use of 2-Chloro-9-[(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)]-9H-purine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.