L-(+)-2-AMINO-6-PHOSPHONOHEXANOIC ACID structure
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Common Name | L-(+)-2-AMINO-6-PHOSPHONOHEXANOIC ACID | ||
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CAS Number | 126253-57-4 | Molecular Weight | 211.153 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 479.3±55.0 °C at 760 mmHg | |
Molecular Formula | C6H14NO5P | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 243.6±31.5 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Name | L-AP6 |
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Synonym | More Synonyms |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 479.3±55.0 °C at 760 mmHg |
Molecular Formula | C6H14NO5P |
Molecular Weight | 211.153 |
Flash Point | 243.6±31.5 °C |
Exact Mass | 211.060959 |
LogP | -2.39 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.529 |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
RIDADR | NONH for all modes of transport |
The lathyrus toxin, beta-N-oxalyl-L-alpha,beta-diaminopropionic acid (ODAP), and homocysteic acid sensitize CA1 pyramidal neurons to cystine and L-2-amino-6-phosphonohexanoic acid.
Toxicol. Appl. Pharmacol. 219 , 1-9, (2007) A brief exposure of hippocampal slices to L-quisqualic acid (QUIS) sensitizes CA1 pyramidal neurons 30- to 250-fold to depolarization by certain excitatory amino acids analogues, e.g., L-2-amino-6-pho... |
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L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization.
Neuroscience 106 , 287-301, (2001) A brief exposure of hippocampal slices to L-quisqualic acid sensitizes CA1 pyramidal neurons 30-250-fold to depolarization by two classes of excitatory amino acid analogues: (1) those whose depolarizi... |
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Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons.
Brain Res. 649 , 203-207, (1994) Brief exposure of rat hippocampal slices to quisqualic acid (QUIS) sensitizes neurons to depolarization by the alpha-amino-omega-phosphonate excitatory amino acid (EAA) analogues AP4, AP5 and AP6. The... |
L-Norleucine, 6-phosphono- |
L-AP6 |
DL-Norleucine, 6-phosphono- |
L-(+)-2-Amino-6-phosphonohexanoic acid |
6-Phosphono-L-norleucine |
MFCD00144531 |