(Rac)-3′-Hydroxy simvastatin

Modify Date: 2023-02-02 07:41:41

(Rac)-3′-Hydroxy simvastatin Structure
(Rac)-3′-Hydroxy simvastatin structure
Common Name (Rac)-3′-Hydroxy simvastatin
CAS Number 126313-98-2 Molecular Weight 434.56600
Density N/A Boiling Point N/A
Molecular Formula C25H38O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (Rac)-3′-Hydroxy simvastatin


(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

 Names

Name 3”-hydroxy simvastatin

 (Rac)-3′-Hydroxy simvastatin Biological Activity

Description (Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
Related Catalog
References

[1]. Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.

 Chemical & Physical Properties

Molecular Formula C25H38O6
Molecular Weight 434.56600
Exact Mass 434.26700
PSA 93.06000
LogP 3.55640
Index of Refraction 1.542