Norgestimate metabolite norelgestromin-d6

Modify Date: 2025-08-25 21:37:20

Norgestimate metabolite norelgestromin-d6 Structure
Norgestimate metabolite norelgestromin-d6 structure
Common Name Norgestimate metabolite norelgestromin-d6
CAS Number 1263184-13-9 Molecular Weight 333.50
Density 1.2±0.1 g/cm3 Boiling Point 491.9±45.0 °C at 760 mmHg
Molecular Formula C21H23D6NO2 Melting Point N/A
MSDS N/A Flash Point 327.1±18.0 °C

 Use of Norgestimate metabolite norelgestromin-d6


Norgestimate metabolite norelgestromin-d6 is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen.

 Names

Name 17-Desacetyl Norgestimate-d6 (Mixture of Isomers)

  Biological Activity

Description Norgestimate metabolite norelgestromin-d6 is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 491.9±45.0 °C at 760 mmHg
Molecular Formula C21H23D6NO2
Molecular Weight 333.50
Flash Point 327.1±18.0 °C
Exact Mass 333.257477
LogP 4.40
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.633
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