CTA 056

Modify Date: 2024-01-11 14:57:27

CTA 056 Structure
CTA 056 structure
Common Name CTA 056
CAS Number 1265822-30-7 Molecular Weight 554.68400
Density N/A Boiling Point N/A
Molecular Formula C35H34N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CTA 056


CTA056 is an ITK (IL-2-inducible T-cell kinase) inhibitor with an IC50 of 0.1 μM. CTA056 selectively targets malignant T cells and modulates oncomirs. CTA056 induces apoptosis and is a potential therapeutic agent for the treatment of T-cell leukemia and lymphoma[1].

 Names

Name 7-benzyl-1-(3-(piperidin-1-yl)propyl)-2-(4-(pyridin-4-yl)phenyl)-1H-imidazo[4,5-g]quinoxalin-6(5H)-one
Synonym More Synonyms

 CTA 056 Biological Activity

Description CTA056 is an ITK (IL-2-inducible T-cell kinase) inhibitor with an IC50 of 0.1 μM. CTA056 selectively targets malignant T cells and modulates oncomirs. CTA056 induces apoptosis and is a potential therapeutic agent for the treatment of T-cell leukemia and lymphoma[1].
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References

[1]. Guo W, et al. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012 Nov;82(5):938-47.

 Chemical & Physical Properties

Molecular Formula C35H34N6O
Molecular Weight 554.68400
Exact Mass 554.27900
PSA 79.70000
LogP 6.40650

 Synonyms

cta-056
cta056
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