Spadin

Modify Date: 2025-09-18 09:06:40

Spadin structure	Common Name	Spadin
	CAS Number	1270083-24-3	Molecular Weight	2012.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉₆H₁₄₂N₂₆O₂₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Spadin

Spadin, a natural peptide derived from a propeptide released in blood, is able to block the TREK-1 (KCNK2 or K2P2.1) channel activity. Spadin binds specifically to TREK-1 with an affinity of 10 nM. Spadin is an efficient antidepressant in mice[1].

Name	Spadin

Description	Spadin, a natural peptide derived from a propeptide released in blood, is able to block the TREK-1 (KCNK2 or K2P2.1) channel activity. Spadin binds specifically to TREK-1 with an affinity of 10 nM. Spadin is an efficient antidepressant in mice[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Jean Mazella, et al. Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS Biol. 2010 Apr 13;8(4):e1000355.

Molecular Formula	C₉₆H₁₄₂N₂₆O₂₂
Molecular Weight	2012.34

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Spadin
Price: Check
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DC Chemicals Limited
China
Product Name: Spadin
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.